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visible, lasting results

Professional serums for microneedling and mesotherapy

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Microneedling serums

Our comprehensive range

Up to €750

per package

9 serums

pharmaceutical quality

± 20min

per session

16

skin indications treated

Innovation and performance

Discover our innovative range of serums for professional microneedling, highly concentrated and packaged in boxes of 10 x 5 ml vials, specially designed for optimum synergy with our C-PEN and electroporation.

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High concentration

Serums with high doses of hyaluronic acid and other powerful active ingredients.

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Wide range

Each C-EM serum is designed to target specific skin problems.

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Safety and purity

Manufactured to strict ISO 91722:2015 standards in a pharmaceutical laboratory in Italy.

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Optimum serum efficacy

2-stage operation

Discover the remarkable effects of our professional microneedling serums, designed to deliver both immediate and long-lasting results:


  1. Immediate effect: Thanks to the high concentration of 3-molecular-weight hyaluronic acid (L/M/H), your customers can immediately see the effects of the treatment on their skin, which is visibly smoother and plumper.
  2. Long-term effect: Gradually, the effect of hyaluronic acid fades, giving way to the effects of the other active ingredients in our professional microneedling serums. These active ingredients address your customers' specific issues and remain visible for several months.

2-stage operation

Complementary techniques

Optimum synergy

Our serums are specially designed to work in synergy with mesotherapy techniques such as microneedling and electroporation:


  • Microneedling: Uses microneedles to create micro-perforations, thus triggering the healing process, which leads to natural activation of collagen and elastin fiber synthesis. Thanks to the micro-channels created by the microneedling mechanism, the skin absorbs the active ingredients** contained in the serum much more easily.
  • Electroporation: Uses electrical impulses to temporarily open the skin's pores, increasing the absorption of active ingredients from serums. These micro-aggressions stimulate fibroblasts to produce more collagen and elastin**.


    These methods optimize product penetration and stimulate skin regeneration, maximizing treatment efficacy.

Optimum synergy

A complete range

Treat up to 16 skin indications!

Because every skin is unique and every one of your customers deserves the best, we have developed a complete range of highly concentrated serums.

With our 9 C-EM you can treat up to 16 skin indications and attract a new clientele looking for excellence and concrete results:**


Our serums are manufactured in our
pharmaceutical laboratory in Italy according to the quality standards ISO 9001:2015 and ISO 22716, the most stringent production standard for cosmetic products, giving them exceptional purity and quality for safe skin care. What's more, all our serums are guaranteed perfume-free, paraben-free, PEG-free, alcohol-free and colorant-free**.

Dehydration and drynessWrinkles and fine linesScars and stretch marksHyperpigmentationImperfectionsSensitivityRednessSkin slackeningPhotoagingLack of radiancePuffiness and dark circlesHair loss

C-EM

Our state-of-the-art formulation

Remarkable efficiency

Proven dual effectiveness: immediate and long-term

Unique formulation

Highly concentrated in pharmaceutical-grade active ingredients

Our state-of-the-art formulation

Customer satisfaction

Immediately visible results for customer satisfaction and loyalty.

Maximum comfort

A feeling of freshness and comfort during and after treatment thanks to soothing active ingredients

Customized care

A complete range of 9 professional serums for microneedling and mesotherapy to treat all skin types and problems.

Skin conditions.

Hydra Repair

Dry, dehydrated skin

Formulated to maximize skin hydration over the long term. It fortifies the skin's moisture barrier, optimizing water retention at the heart of the tissues. From the very first application, skin looks radiant, visibly smoothed and plumped thanks to its high concentration of hyaluronic acid and Glucosamine, for a healthy, revitalized appearance.
  • Indication
    • Dehydration
    • Dry skin
    • Fine lines and wrinkles
    • Scars
  • Active ingredients
    • Hyaluronic Acid
    • Vitamin B5
    • Glucosamine
    • Niacinamides
    • Lactic Acid
    • Allantonine
  • All ingredients

    Aqua, Niacinamide, Sodium Hyaluronate, Glycerin, Glucosamine Sulphate, Calcium Pantothenate, Lactic Acid, Phenoxyethanol, Allantoin, Polysorbate 20, Pseudoalteromonas Ferment Extract, Linseed Acid, Saccharo- myces Cerevisiae Extract, Saccharide Isome- rate, Ammonium Acryloyldimethyltaurate/ Vp Copolymer, Imidazolidinyl Urea, Capry- lyl Glycol, Xanthan Gum, Hyaluronic Acid, Butylene Glycol, Ethylhexylglycerin, 1,2-Hexa nediol, Proline, Serine, Alanine, Silanetriol, Sorbic Acid, Sodium Hydroxide, Acetyl Heptapeptide-4, Citric Acid, Sodium Phosphate, Sodium Citrate.

Sensitive care

Sensitive and reactive skin

Formulated with calming and protective active ingredients, this serum is specially designed to reduce redness, irritation and itching. Thanks to the highly soothing properties of bilberry extract and brown seaweed, it is perfectly suited to the most sensitive, delicate and demanding skin, offering immediate relief and reinforced protection against external aggressions.
  • Indication
    • Sensitive skin
    • Redness and couperose
    • Inflammations
    • Itching
    • Rosacea
  • Active ingredients
    • Hyaluronic Acid
    • Vitamin C
    • Bilberry extract
    • Glucosamine
    • Peptides
    • Red and Brown Algae
  • All ingredients

    Aqua, Sodium Hyaluronate, Ascorbic Acid, Vac- cinium Myrtillus Extract, Linseed Acid, Butylene Glycol, Sorbitol, Maltodextrin, Allantoin, Aspara- gopsis Armata Extract, Malus Domestica Fruit Cell Culture Extract, Ascophyllum Nodosum Extract, Pseudo-alteromonas Ferment Extract, Ceramide 3, Phenoxyethanol, Polysorbate 20, Glycerin, Am- monium Acryloyldimethyltaurate Vp Copolymer, Sodium Lauroyl Lactylate, Imidazolidinyl Urea, Xanthan Gum, Caprylyl Glycol, Palmitoyl Tripep- tide-8, Dextran, Ethylhexylglycerin, Cholesterol, Ceramide 6 Ii, Phytosphingosine, Hyaluronic Acid, Silanetriol, Melatonin, Citric Acid, Lecithin, Serine, Alanine, Proline, Glycine Soja Oil, Acetyl Tetrapeptide-40, Acetyl Heptapeptide-4, Hydro- genated Lecithin, Ceramide 1, Sh-Polypeptide-9, Carbomer, Sodium Phosphate, Sodium Oleate, Disodium Edta, Sodium Hydroxide, Potassium Sorbate, Sorbic Acid.

Imperfections.

Hyper pigment

Spots and uneven skin tone

Designed to effectively address all types of pigmentation spots, including those resulting from photoaging and melasma, as well as complexion irregularities, this advanced serum offers immediate brightening visible from the very first application. It works to restore perfect evenness and revive skin's natural radiance by actively targeting discoloration and hyperpigmentation. Thanks to its innovative active ingredients, it limits melanin production, ensuring a lasting improvement in skin evenness and luminosity.
  • Indication
    • Uneven skin tone
    • Hyperpigmentation
    • Melasma / Chloasma
    • Various spots
    • Photoaging
  • Active ingredients
    • Phytic Acid
    • Kojic Acid
    • Azelaic Acid
    • α-Arbutin
    • Rapeseed extract
    • Allantoin
    • Glucosamine
    • Peptides
  • All ingredients

    Aqua, -Arbutin, Niacinamide, Azelaic Acid, Kojic Acid, Sodium Hyaluronate, Phytic Acid, Glycerin, Hydroxyethylcellulose, Glucosamine Sulphate, Tranexamic Acid, Allantoin, Hydro- lized Brassica Napus Seedcake Extract, Hya- luronic Acid, Ammonium Acryloyldimethyl- taurate/Vp Copolymer, Phenoxyethanol, Imi- dazolidinyl Urea, Silanetriol, Sh-Polypeptide- 11, Sh-Polypeptide-1, Citric Acid, Butylene Glycol, Sodium Oleate, Glycine Soja Oil, Hydrogenated Lecithin, Disodium Edta, Sorbic Acid.

Pure Clean

Oily skin and blemishes

PureClean's powerful active ingredients are specially selected to soothe skin reactions, gently moisturize and regulate sebum secretion with remarkable precision, effectively preventing the appearance of new breakouts while significantly reducing existing imperfections. This innovative treatment is the key to visibly smoother, more even skin.
  • Indication
    • Blemishes
    • Excess sebum
    • Dilated pores
    • Blackheads
    • Blackheads
    • Acne scars
    • Bacterial inflammation
  • Active ingredients
    • Hyaluronic Acid
    • Royal Jelly extract
    • Nettle Protein
    • Aloe Vera
    • Burdock
    • Tripeptides
  • All ingredients

    Aqua, Butylene Glycol, Peg-40 Hydrogenated Castor Oil, Sodium Hyaluronate, Niacinamide, Ethoxydi- glycol, Aloe Barbadensis Leaf Juice Powder, 10-Hydroxydecanoic Acid, Sebacic Acid, 1,10- Decanediol, Hydrolyzed Nettle Leaf Extract, Chlorhexidine Digluconate, Glycerin, Arctium Lappa Root Extract, Hyaluronic Acid, Phenoxyethanol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Palmitoyl Tripeptide-8, Sodium Salicylate, Dextran, Imidazolidinyl Urea, Sorbic Acid, Citric Acid, Silanetriol, Potassium Sorbate.

Anti-aging.

EGF Regen

Marked skin and loss of firmness

Specially designed for sensitive and combination skin showing advanced signs of aging or blemishes. Each ingredient has been meticulously selected for its unique properties and its complementarity with the others. Enriched with hyaluronic acid, this serum offers an immediate plumping and smoothing effect. EGF/IGF stimulate cell repair and collagen production, visibly reducing wrinkles. Glucosamine improves epidermal firmness, while soybean oil extract selectively moisturizes, ensuring an even, radiant complexion.
  • Indication
    • Deep wrinkles
    • Sagging skin
    • Signs of aging
    • Scars
    • Stretch marks
  • Active ingredients
    • Hyaluronic acid
    • Epidermal growth factors (EGF & IGF)
    • Copper tripeptides
    • Polypeptides
    • Argireline
  • All ingredients

    Aqua, Sodium Hyaluronate, Glycerin, Sac- charomyces Cerevisiae Extract, Saccharide Isomerate, Hyaluronic Acid, Hydroxypropyl Cyclodextrin, Ammonium Acryloyldimethyl- taurate/Vp Copolymer, Hydrogenated Lecithin, Sodium Oleate, Phenoxyethanol, Imidazolidinyl Urea, Butylene Glycol, Caprylyl Glycol, Glycine Soja Oil, Palmitoyl Tripeptide-38, Citric Acid, Silanetriol, Acetyl Tetrapeptide-40, Acetyl Hexapeptide-8, Sh-Oligopeptide-1, Copper Tripeptide-1, Sh-Oligopeptide- 2, Sh-Poly- peptide-3, Sodium Citrate, Sodium Benzoate, Sorbic Acid, 1,2-Hexanediol, Disodium Edta.

BTX Effect

Loose skin and loss of elasticity

To counter expression lines and loss of firmness, C-EM BTX effect is an effective, straightforward solution. Its rich hyaluronic acid content ensures an immediate smoothing effect on the skin. The inclusion of argireline and peptides specifically targets the density and depth of expression lines, offering a noticeable reduction. Used with microneedling, this serum is perfect for an express beauty makeover before a major event, promising immediate results that will strengthen over time.
  • Indication
    • Expression lines
    • Lack of elasticity
    • Loss of firmness
  • Active ingredients
    • Hyaluronic Acid
    • DMAE
    • Glucosamine
    • BTX Peptides
  • All ingredients

    Aqua, Glycerin, Sodium Hyaluronate, Dimethyl- aminoethanol Tartrate, Glucosamine Sulphate, Ammonium Acryloyldimethyltaurate/Vp Copo- lymer, Caprylyl Glycol, Hyaluronic Acid, Pheno- xyethanol, Dipeptide Diaminobutyroyl Benzyl- amide Diacetate, Palmitoyl Tripeptide-38, Acetyl Octapeptide-3, Pentapeptide-18, Acetyl Hexapeptide- 8, Silanetriol, Hydroxypropyl Cyclodextrin, Butylene Glycol, Citric Acid, Imidazolidinyl Urea, Sodium Benzoate, Sorbic Acid.

AOX Repair

Stressed skin and photoaging

Formulated to combat photoaging and everyday impacts on the skin, such as stress and pollution. Enriched with ingredients with powerful antioxidant properties such as vitamin C and niacinamides, this serum offers effective protection against external aggressors, while restoring skin hydration and promoting epidermal regeneration thanks to retinol, for revitalized, protected skin.
  • Indication
    • Dull complexion
    • Dryness
    • Photoaging
    • Various blemishes
    • Wrinkles caused by daily life (stress, pollution, toxins, etc.)
  • Active ingredients
    • Hyaluronic Acid
    • Niacinamide (Vit.B3)
    • Vitamin C
    • Retinol (Vit.A)
    • Alpha-Lipoic Acid
    • Physalis extract
  • All ingredients

    Aqua, Polysorbate 20, Niacinamide, Caprylic/ Capric Triglyceride, 3-O-Ethyl Ascorbic Acid, Sodium Hyaluronate, Physalis Angulata Extract, Retinol, Dimethyl Isosorbide, Thioctic Acid, Ferulic Acid, Hydroxymethoxyphenyl Deca- none, Hydroxypinacolone Retinoate, Pheno- xyethanol, Imida-zolidinyl Urea, Dimethyl- methoxy Chromanol, Ammonium Acryloyl- dimethyltaurate/Vp Copolymer, Melatonin, Cyanocobalamin, Hyaluronic Acid, Silanetriol, Citric Acid, Tocopherol, Lycopene, Sorbic Acid, Butylene Glycol, Bht, Disodium Edta.

Special.

Eye Perfect

Eye contour  

A serum specially designed for the eye contour area, with a dual action on puffiness, dark circles and wrinkles. First, hyaluronic acid helps to smooth the eye contour and rehydrate the area. Peptides then stimulate collagen production to smooth wrinkles and restore skin elasticity. Finally, caffeine improves blood circulation to combat puffiness and puffiness.
  • Indication
    • Pockets
    • Dark circles
    • Crow's feet
    • Fine lines around the eyes
    • Slack eyelids
  • Active ingredients
    • Hyaluronic Acid
    • Vitamin C
    • Niacinamide (Vit.B3)
    • Peptides
    • Haloxyl
    • Glucosamine
  • All ingredients

    Aqua, Sodium Hyaluronate, Ascorbyl Tetra- isopalmitate, Niacinamide, Glucosamine Sul- phate, Lecithin, Glycerin, Caffeine, Ruscus Acu- leatus Root Extract, Tea-Hydroiodide, Malus Domestica Fruit Cell Culture Extract, Acacia Senegal Gum, Carnitine, Helianthus Annuus Seed Oil, Hyaluronic Acid, Escin, Hedera Helix Leaf/Stem Extract, Phenoxyethanol, Butylene Glycol, Ammonium Acryloyldimethyltaurate/ Vp Copolymer, Imidazolidinyl Urea, Silane- triol, Steareth-20, Caprylyl Glycol, Malto- dextrin, Hydrated Silica, Citric Acid, N-Hydro- xysuccinimide, Chrysin, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Tetrapeptide- 5, Carrageenan, Ascorbyl Palmitate, Tripep- tide-1, Menaquinone-7, Xanthan Gum, Potassium Sorbate, Sorbic Acid.

Hair Growth

Hair loss and density loss

This advanced formulation combines biomimetic growth factors and a vitamin complex to actively stimulate the proliferation of stem cells and their evolution into hair follicles. The beneficial effect is a significant slowdown in hair loss and an acceleration in hair growth, promoting denser, longer hair or beard.
  • Indication
    • Slow regrowth
    • Severe hair loss
    • Loss of hair mass
    • Tired hair bulbs
    • Beard density problems
  • Active ingredients
    • Hyaluronic acid
    • Growth factors (VEGF, EGF, KGF, IGF,FGF)
    • Copper tripeptides
    • Cyanocobalamin
  • All ingredients

    Aqua, Sodium Hyaluronate, Ammonium Acryloyldimethyltaurate/vp Copolymer, Cyanocobalamin, Hydrogenated Lecithin, Sodium Oleate, Glycine- Soja Oil, Glycerin, Sh-Oligopeptide-2, Sh-polypeptide-1, Sh-polypeptide-11, Copper Tripeptide-1, Sh-Polypeptide-3, Sh-Polypeptide-9, Hyalu- ronic Acid, Butylene Glycol, Silanetriol, Phenoxyethanol, Imidazolidinyl Urea, CitricAcid, Sorbic Acid, Disodium Edta.

Our professional equipment.

C-PEN III

Microneedling

Build customer loyalty by offering them a revolutionary solution for their skin. With the C-PEN III, celestetic's Professional Automatic Micro Needler, you have the secret weapon for dazzling, rejuvenated skin!
  • Benefits
    • Biophysical stimulation
    • Cell regeneration
    • Chemical stimulation
  • Functionalities
    • Nano or 16 needles
    • 2 rechargeable batteries
    • 6 speeds to choose from
    • Adjustable depth from to 2.5 mm

Meso+ II

Electroporation

Give your customers sublimated skin without needles or pain! Reinvent electroporation with precision and innovation thanks to Meso+ II
  • Benefits
    • Asset penetration in excess of 80%.
    • Generation of micro-channels
    • Stimulation of fibroblasts
  • Functionalities
    • Temperature range -5 to +45°C
    • Continuous or pulse mode
    • Lightweight 5kg unit
What our customers say

Hundreds of institutes place their trust in us.

A must-have for my salon

Ever since I introduced C-PEN with C-EM serums in my institute, my customers have been amazed by the results. Their skin is visibly smoother and firmer after each session. It's a worthwhile investment.

— Mei Ling
Oriental beauty

Visible, lasting results

My customers are always amazed to see results immediately after the treatment. And these results become more and more visible as the days go by, up to 6 weeks after the treatment. It's truly impressive.

— Ingrid S
Svensson Esthétique

Needle-free mesotherapy

These serums are perfectly suited to mesotherapy with or without needles, which is why I recommend them to all my customers.

— Lydia R
Solidya

Why choose Celestetic's range of professional serums for microneedling and mesotherapy?

At Celestetic, we offer a complete range of professional microneedling serums specially designed to deliver visible, long-lasting results.

Our C-EM serums, ultra-concentrated and dosed with hyaluronic acid and other powerful active ingredients, meet the specific needs of every skin type. Whether you have oily skin, redness, expression lines, or suffer from loss of elasticity, there's a microneedling serum in our range that will effectively address these issues.


Our products are formulated for optimal use during professional microneedling or facial mesotherapy sessions. Thanks to a high concentration of hyaluronic acid, our serums promote deep hydration and enhanced cell regeneration. Whether you're looking for the best microneedling serum, a product for professional microneedling, or a kit for professional microneedling, our range ensures effective care with visible results from the very first session.


Microneedling is one of the most effective techniques for treating wrinkles, dark circles, brown spots, and even problems such as cellulite. Our microneedling serums work in synergy with the latest technologies, such as C-PEN III, to maximize absorption of active ingredients and stimulate natural collagen production. So you can treat areas like the around the eyes, where microneedling reduces under-eye puffiness and circles, or improve the appearance of stretch marks and body contour**.

Whether you're looking for a mesotherapy facial product, a serum for hyaluronic acid microneedling, or wondering which serum to use for microneedling, Celestetic has the right solution for every problem. Our serums are fragrance-free, paraben-free, PEG-free, alcohol-free and colorant-free, guaranteeing safe care for even the most sensitive skin.


You can purchase our microneedling products directly via our website or from our authorized distributors. Prices vary according to the treatment and serum chosen, but every professional microneedling kit guarantees immediate and long-term results.


In short, the C-EM range is the ideal choice for all beauty professionals looking for safe, effective microneedling and mesotherapy solutions to suit every skin type. Whether it's to combat wrinkles, redness, or imperfections, our serums are the perfect answer for immediate and long-term visible results.

FAQ about C-EM sera

Your questions about celestetic professional microneedling serums.

  • 1. What are the main advantages of C-EM serums for microneedling and needle-free mesotherapy?

    C-EM serums offer both immediate and long-term efficacy, thanks to a high concentration of hyaluronic acid and other powerful active ingredients. Their formula is designed to maximize the absorption of active ingredients during microneedling or needle-free mesotherapy treatments, enhancing hydration, cell regeneration, and collagen and elastin production. In addition to providing rapidly visible results, the effects last for several months.

  • 2. How many types of C-EM serums are there and what skin problems do they treat?

    There are 9 C-EM serums, each targeting specific skin problems:

    • Hydra Repair: Dehydrated, dry skin.
    • Sensitive Care: Sensitive and reactive skin.
    • Hyperpigment: Pigmentation spots and uneven skin tone.
    • Pure Clean: Oily skin and imperfections.
    • EGF Regen: Deep wrinkles, scars, sagging skin.
    • BTX Effect: Expression lines, loss of elasticity and firmness.
    • AOX Repair: Stressed skin and photoaging.
    • Eye Perfect: Dark circles, puffiness and fine lines around the eyes.
    • Hair Growth: Hair loss and loss of density.
  • 3. Are C-EM serums suitable for all skin types?

    Yes, C-EM serums are formulated to suit all skin types. They address a wide range of concerns, such as dryness, wrinkles, imperfections, loss of elasticity, and pigmentation spots. Each serum is designed to meet the specific needs of even the most delicate skin, while ensuring maximum effectiveness.

  • 4. How do I use C-EM serums during a needle-free mesotherapy session?

    For a needle-free mesotherapy session, apply the selected serum to clean, makeup-free skin. Use a mesotherapy device, such as electroporation, or combine it with a microneedling treatment. The device will enhance the penetration of the serum's active ingredients by increasing the skin's permeability. Be sure to tailor the serum to the customer's specific problem for optimal results.

  • 5. What results can you expect from C-EM sera, and how long will it take?

    Results are visible from the very first session, with an immediate plumping and smoothing effect thanks to the concentration of hyaluronic acid. Long-term effects, such as improved firmness and reduced wrinkles and imperfections, appear over the course of several weeks. A complete treatment, often consisting of 6 sessions, can prolong and intensify the benefits over several months.

  • 6. Are there any special precautions to be taken when using C-EM sera?

    It's important to apply C-EM serums to clean, makeup-free skin. After treatment, we recommend protecting the skin from the sun with sunscreen and avoiding irritating products for a few days. Each serum is formulated without parabens, PEGs, alcohol or colorants, which minimizes the risk of reactions, but it is advisable to test on a small area for particularly sensitive skin.

  • 7. Where can I buy C-EM serums and how much do they cost?

    C-EM serums are available for sale on the Celestetic website or from authorized distributors. Prices may vary according to serum type and sales conditions, but it is generally advisable to offer packages of several sessions for optimum results. Individual sessions can cost between €45 and €125, and a complete package of 6 sessions can cost up to €750, depending on the customer's specific needs.

Questions we haven't answered?

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Géraldine

Don't hesitate to contact our advisors with any questions you may have! They are ready to listen and guide you towards the best solutions for your needs.

no miracle, just science.

Celestetic is Belgium's leading medi-aesthetics laboratory. Our mission is to combine technological innovations with scientific advances to bring to market products and professional solutions that are truly effective for the skin. No false promises, no stories. With transparency and honesty.

Professional training

For perfect mastery of techniques

Product quality

Ingredients whose effectiveness has been scientifically proven

Solid, high-quality follow-up

We support you over the long term and listen to your needs

Compliance with European standards

Appliances and products designed to comply with European laws and standards

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